Resources Avalaible via London Genetics
Samples for Genetic Investigation, Data to Interrogate
- DNA samples, -omic and biomarker samples collected from well-characterised patients across a range of therapeutic areas and ethnic groups
- Genetic information for data mining
Patient Cohorts for Marker Discovery and Inclusion in Clinical Trials
- Well-characterised
patient cohorts
across a range of therapeutic areas available for marker discovery and
confirmation
- Well-characterised patient networks for recruitment into clinical trials
- Ethnically diverse populations
- Therapeutic area cohorts available via London Genetics
(COPD - chronic obstructive pulmonary disease CHD - chronic heart disease)
Networks of Clinical, Genetic and Bioinformatics Experts
- Worldwide clinical, genetic and bioinformatic experts for participation in key opinion leader meetings and advisory meetings, to facilitate drug development
Drug Development Expertise Available
- Investigator-led research and clinical development programmes Based on experience in leading clinical development programmes, design and study planning, and study implementation expertise is available
- Project management: Ensuring effective and timely delivery of projects
- Data management: management of the large complex data sets rising from genetic studies
- Consultancy and strategic planning: advice on how, when and where to apply pharmacogenetics to clinical development, including which genetic hypotheses to test, and the type and timing of samples
Data and Laboratory Services
- Statistical genetics: Analysis and interpretation of data, Phase III planning
- Sample analysis (DNA, RNA and proteomic): full analysis support across a range of genetic and genomic markers, including DNA sequencing, genotyping, and expression analysis:
- DNA genotyping/sequencing
- Transcriptomics
- Proteomics
- Epigenetics